STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0736Mannose-6-phosphate isomerase; Similar to GB:U02562 SP:P39841 PID:1129073 PID:476092 GB:AL009126 percent identity: 56.25; identified by sequence similarity; putative. (278 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Similar to GB:L77117 PID:1500502 percent identity: 61.52; identified by sequence similarity; putative.
 
 
 0.996
TM_0769
Phosphomannomutase; Similar to GB:M34393 SP:P18159 PID:142994 PID:2226139 GB:AL009126 percent identity: 59.49; identified by sequence similarity; putative.
 
 
 0.994
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.992
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub- subfamily.
 
  
 0.992
pfp
6-phosphofructokinase, pyrophosphate-dependent; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II s [...]
    
 0.991
TM_0296
Fructokinase; Similar to PID:1052973 percent identity: 57.14; identified by sequence similarity; putative.
    
 0.991
TM_0813
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 56.91; identified by sequence similarity; putative.
    
  0.991
TM_1033
Mannose-1-phosphate guanylyltransferase; Similar to GB:L11721 SP:P24174 GB:M77127 PID:147164 PID:304878 percent identity: 60.42; identified by sequence similarity; putative.
 
 0.938
glk
Glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. Can also phosphorylate 2- deoxyglucose, with lower efficiency. ITP can also serve as a phosphoryl donor.
 
 
 0.910
TM_0735
Conserved hypothetical protein; Similar to PID:1165252 GB:AE000783 percent identity: 49.78; identified by sequence similarity; putative.
       0.827
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.