STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0772Conserved hypothetical protein; Similar to GB:D26185 SP:P37541 PID:467422 GB:AL009126 percent identity: 66.12; identified by sequence similarity; putative. (271 aa)    
Predicted Functional Partners:
TM_0771
DNA polymerase III, gamma subunit-related protein; Similar to GB:AE000657 percent identity: 56.32; identified by sequence similarity; putative.
  
   0.840
TM_0773
Hypothetical protein; Identified by sequence similarity; putative.
       0.810
TM_0774
Conserved hypothetical protein; Similar to SP:P32729 GB:Z18631 PID:49318 GB:AL009126 percent identity: 56.38; identified by sequence similarity; putative.
       0.810
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.761
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
    0.752
rny
Conserved hypothetical protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
  
 0.750
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
      0.731
TM_0770
Conserved hypothetical protein; Similar to PID:1652365 percent identity: 62.39; identified by sequence similarity; putative.
 
     0.652
rbgA
Conserved hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. Binds to the 23S rRNA (By similarity). Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
       0.578
TM_0769
Phosphomannomutase; Similar to GB:M34393 SP:P18159 PID:142994 PID:2226139 GB:AL009126 percent identity: 59.49; identified by sequence similarity; putative.
       0.578
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.