Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TM_0795Sugar kinase, pfkB family; Similar to SP:P36945 GB:Z25798 PID:397495 PID:1894761 GB:AL009126 percent identity: 45.34; identified by sequence similarity; putative. (270 aa)    
Predicted Functional Partners:
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
  
  0.803
prs
Phosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.696
TM_1762
Transketolase, putative; Similar to GP:452486 percent identity: 53.52; identified by sequence similarity; putative.
   
 0.664
TM_1080
Sugar-phosphate isomerase; Similar to GB:AE000657 percent identity: 77.62; identified by sequence similarity; putative.
    
 0.656
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
    
 0.643
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
     
  0.625
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
 
  
 0.571
TM_0796
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 54.55; identified by sequence similarity; putative.
       0.560
comB
Conserved hypothetical protein; Similar to GP:2622290 percent identity: 59.13; identified by sequence similarity; putative; Belongs to the ComB family.
       0.560
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Similar to GB:M90760 SP:Q02131 PID:149382 percent identity: 56.30; identified by sequence similarity; putative; Belongs to the HisA/HisF family.
  
    0.538
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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