STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0807Alkyl hydroperoxide reductase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (215 aa)    
Predicted Functional Partners:
TM_0996
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 72.37; identified by sequence similarity; putative.
  
 0.988
TM_0868
Glutaredoxin-related protein; Similar to PID:840852 percent identity: 68.35; identified by sequence similarity; putative.
  
  
 0.960
TM_0134
Thioredoxin reductase-related protein; Similar to GB:L04500 PID:388294 SP:P50971 PID:1353197 percent identity: 54.05; identified by sequence similarity; putative.
  
 
 0.873
TM_0869
Thioredoxin reductase; Similar to GB:Pyro_h percent identity: 67.62; identified by sequence similarity; putative.
  
 
 0.873
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
  
 
 0.717
TM_1128
Ferritin; Iron-storage protein.
  
  
 0.625
TM_0386
Bacterioferritin comigratory protein/NADH dehydrogenase; Similar to PID:1651777 percent identity: 59.42; identified by sequence similarity; putative.
 
 
 0.615
groL
groEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.596
TM_0657
Rubrerythrin; Similar to GB:AE000782 percent identity: 74.55; identified by sequence similarity; putative.
  
  
 0.596
grpE
grpE protein, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-d [...]
   
 
 0.590
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.