STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0813Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 56.91; identified by sequence similarity; putative. (330 aa)    
Predicted Functional Partners:
TM_0814
N-acetylglucosamine-6-phosphate deacetylase; Similar to GB:AL009126 percent identity: 56.57; identified by sequence similarity; putative.
  
 
 0.999
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
0.995
glmM
Phosphoglucomutase/phosphomannomutase family protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
  0.994
glnA
Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under [...]
  
  
 0.993
TM_0296
Fructokinase; Similar to PID:1052973 percent identity: 57.14; identified by sequence similarity; putative.
  
 
 0.992
TM_0736
Mannose-6-phosphate isomerase; Similar to GB:U02562 SP:P39841 PID:1129073 PID:476092 GB:AL009126 percent identity: 56.25; identified by sequence similarity; putative.
    
  0.991
pgi
Glucose-6-phosphate isomerase; Similar to GB:L77117 PID:1500502 percent identity: 61.52; identified by sequence similarity; putative.
    
  0.991
TM_0811
Sugar ABC transporter, permease protein; Similar to PID:1652461 percent identity: 68.25; identified by sequence similarity; putative.
  
    0.777
TM_0812
Sugar ABC transporter, permease protein, putative; Similar to PID:1652996 percent identity: 63.26; identified by sequence similarity; putative.
  
    0.764
TM_0808
Transcriptional regulator, XylR-related; Similar to PID:1924925 PID:2398723 percent identity: 52.25; identified by sequence similarity; putative.
    
  0.673
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.