STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0820NADH-dependent butanol dehydrogenase, putative; Similar to GB:AL009126 percent identity: 68.22; identified by sequence similarity; putative. (395 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.807
TM_0819
Uracil permease; Similar to GB:X76083 SP:P41006 PID:431231 percent identity: 69.41; identified by sequence similarity; putative.
       0.678
pheT
phenylalanyl-tRNA synthetase, beta subunit; Similar to GB:AE000657 percent identity: 61.38; identified by sequence similarity; putative; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.641
TM_0818
Lipopolysaccharide biosynthesis protein, putative; Similar to GP:2209208 percent identity: 60.39; identified by sequence similarity; putative; Belongs to the glycosyltransferase 26 family.
       0.537
gap
Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG (By similarity). Belongs to the glyceraldehyde-3-phospha [...]
 
    
 0.534
TM_0920
Alcohol dehydrogenase, iron-containing; Similar to GB:AE000657 percent identity: 57.73; identified by sequence similarity; putative.
  
  
0.532
pheS
phenylalanyl-tRNA synthetase, alpha subunit; Similar to GB:AL009126 percent identity: 73.25; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
       0.476
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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