Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TM_0823Transcriptional regulator, TetR family; Similar to GB:AE000657 percent identity: 53.14; identified by sequence similarity; putative. (190 aa)    
Predicted Functional Partners:
TM_0824
astB/chuR-related protein; Similar to GB:AE000782 percent identity: 51.47; identified by sequence similarity; putative.
  
    0.788
TM_0825
astB/chuR-related protein; Similar to GB:AE000782 percent identity: 55.52; identified by sequence similarity; putative.
  
    0.550
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.525
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.523
TM_0827
ABC transporter, ATP-binding protein, putative; Similar to PID:2108228 percent identity: 57.14; identified by sequence similarity; putative.
 
     0.494
ftsA
Cell division protein FtsA, putative; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
 
   
 0.479
TM_1184
pleD-related protein; Similar to PID:1652841 percent identity: 50.78; identified by sequence similarity; putative.
  
 
 0.471
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.457
TM_0756
Galactosyltransferase-related protein; Similar to GP:2198543 percent identity: 61.83; identified by sequence similarity; putative.
     
 0.455
TM_0482
(R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; Similar to GB:L77117 SP:Q58210 PID:1591496 percent identity: 53.49; identified by sequence similarity; putative.
 
   
 0.445
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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