STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0825astB/chuR-related protein; Similar to GB:AE000782 percent identity: 55.52; identified by sequence similarity; putative. (323 aa)    
Predicted Functional Partners:
TM_0824
astB/chuR-related protein; Similar to GB:AE000782 percent identity: 51.47; identified by sequence similarity; putative.
 
    
0.617
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
  
 
  0.613
TM_0823
Transcriptional regulator, TetR family; Similar to GB:AE000657 percent identity: 53.14; identified by sequence similarity; putative.
  
    0.550
TM_0826
Hypothetical protein; Identified by sequence similarity; putative.
       0.550
TM_0827
ABC transporter, ATP-binding protein, putative; Similar to PID:2108228 percent identity: 57.14; identified by sequence similarity; putative.
       0.534
gyrB
DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.510
mtaB
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. Belongs to the methylthiotransferase family. MtaB subfamily.
  
  
 0.499
TM_0842
Response regulator; Similar to PID:1651932 percent identity: 56.68; identified by sequence similarity; putative.
 
  
 0.491
TM_0828
Sugar kinase, pfkB family; Similar to SP:P11099 GB:X14827 PID:46605 percent identity: 54.05; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
       0.472
TM_0829
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58821 PID:1592076 percent identity: 60.77; identified by sequence similarity; putative.
       0.472
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.