STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0827ABC transporter, ATP-binding protein, putative; Similar to PID:2108228 percent identity: 57.14; identified by sequence similarity; putative. (234 aa)    
Predicted Functional Partners:
TM_1137
Branched chain amino acid ABC transporter, permease protein; Similar to GB:D90223 SP:P21628 GB:M64046 PID:216865 percent identity: 62.72; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
  
 
 0.855
TM_1136
Branched chain amino acid ABC transporter, permease protein; Similar to GB:D12589 SP:P30295 GB:X52093 PID:217072 percent identity: 68.09; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
  
 
 0.847
TM_0826
Hypothetical protein; Identified by sequence similarity; putative.
       0.773
TM_1139
Branched chain amino acid ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 74.48; identified by sequence similarity; putative.
  
 
 0.773
TM_1135
Branched chain amino acid ABC transporter, periplasmic amino acid-binding protein; Similar to SP:P04816 GB:U00039 GB:J01644 GB:M29378 GB:V00301 percent identity: 49.86; identified by sequence similarity; putative.
  
 
 0.742
mtaB
Conserved hypothetical protein; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. Belongs to the methylthiotransferase family. MtaB subfamily.
       0.741
TM_0828
Sugar kinase, pfkB family; Similar to SP:P11099 GB:X14827 PID:46605 percent identity: 54.05; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
       0.737
ilvE
Branched-chain amino acid aminotransferase, putative; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
       0.736
gyrB
DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.736
TM_0832
Hypothetical protein; Identified by sequence similarity; putative.
       0.735
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.