STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0842Response regulator; Similar to PID:1651932 percent identity: 56.68; identified by sequence similarity; putative. (253 aa)    
Predicted Functional Partners:
TM_0906
Conserved hypothetical protein; Similar to PID:1185065 GB:AE000783 percent identity: 58.89; identified by sequence similarity; putative.
  
 0.925
cheA
Chemotaxis sensor histidine kinase CheA; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY (By similarity).
 
 0.914
fliM
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheX chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
  
 
 0.884
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 
 0.853
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.853
TM_0907
Flagellar biosynthesis protein FlhF; Similar to SP:Q01960 GB:X66445 PID:39919 GB:AL009126 percent identity: 65.48; identified by sequence similarity; putative.
  
  
 0.851
fliG
Flagellar motor switch protein FliG; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
  
  
 0.830
TM_0219
Flagellar export/assembly protein; Similar to PID:2105150 percent identity: 58.22; identified by sequence similarity; putative.
  
 
 0.815
TM_0843
Formiminotransferase- cyclodeaminase/formiminotetrahydrofolate cyclodeaminase, putative; Similar to SP:P53603 PID:433003 percent identity: 63.70; identified by sequence similarity; putative.
       0.810
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.810
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.