STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmHConserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (151 aa)    
Predicted Functional Partners:
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.830
TM_0843
Formiminotransferase- cyclodeaminase/formiminotetrahydrofolate cyclodeaminase, putative; Similar to SP:P53603 PID:433003 percent identity: 63.70; identified by sequence similarity; putative.
       0.815
TM_0842
Response regulator; Similar to PID:1651932 percent identity: 56.68; identified by sequence similarity; putative.
       0.813
era
Conserved hypothetical protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
     0.784
TM_0845
Hemolysin-related protein; Similar to GB:AE000783 percent identity: 61.61; identified by sequence similarity; putative.
       0.777
TM_0846
Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
       0.776
TM_0848
Conserved hypothetical protein; Similar to SP:P54453 PID:1303788 GB:AL009126 percent identity: 57.89; identified by sequence similarity; putative.
  
    0.721
TM_0841
S-layer-like array protein; Similar to PID:993026 percent identity: 56.08; identified by sequence similarity; putative.
       0.667
TM_0840
Hypothetical protein; Identified by sequence similarity; putative.
       0.632
TM_0839
Rod shape-determining protein RodA; Similar to GB:AE000657 percent identity: 63.05; identified by sequence similarity; putative; Belongs to the SEDS family.
     
 0.607
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.