STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0845Hemolysin-related protein; Similar to GB:AE000783 percent identity: 61.61; identified by sequence similarity; putative. (455 aa)    
Predicted Functional Partners:
era
Conserved hypothetical protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
    0.863
TM_0846
Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.836
TM_0843
Formiminotransferase- cyclodeaminase/formiminotetrahydrofolate cyclodeaminase, putative; Similar to SP:P53603 PID:433003 percent identity: 63.70; identified by sequence similarity; putative.
       0.789
TM_0842
Response regulator; Similar to PID:1651932 percent identity: 56.68; identified by sequence similarity; putative.
       0.772
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.772
TM_0848
Conserved hypothetical protein; Similar to SP:P54453 PID:1303788 GB:AL009126 percent identity: 57.89; identified by sequence similarity; putative.
  
    0.767
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.752
TM_0841
S-layer-like array protein; Similar to PID:993026 percent identity: 56.08; identified by sequence similarity; putative.
 
     0.721
TM_0840
Hypothetical protein; Identified by sequence similarity; putative.
       0.603
TM_1601
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 62.14; identified by sequence similarity; putative.
  
     0.527
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.