Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TM_0866Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 75.26; identified by sequence similarity; putative. (305 aa)    
Predicted Functional Partners:
TM_0865
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 62.69; identified by sequence similarity; putative.
 
 
 0.962
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
   
 0.815
TM_0867
Hypothetical protein; Identified by sequence similarity; putative.
       0.813
TM_0864
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58897 PID:1592137 percent identity: 52.03; identified by sequence similarity; putative.
  
   0.789
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
  
    0.782
TM_0869
Thioredoxin reductase; Similar to GB:Pyro_h percent identity: 67.62; identified by sequence similarity; putative.
  
  
 0.744
TM_0868
Glutaredoxin-related protein; Similar to PID:840852 percent identity: 68.35; identified by sequence similarity; putative.
       0.734
mtaD
Conserved hypothetical protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Adenosine-5-monophosphate (AMP) and S-adenosyl-L-methionine (SAM) are not enzyme substrates.
      0.662
TM_1346
Processing protease, putative; Similar to SP:Q04805 percent identity: 51.10; identified by sequence similarity; putative; Belongs to the peptidase M16 family.
  
 0.547
TM_0862
Glucose-1-phosphate thymidylyltransferase; Similar to PID:1001492 PID:1001590 percent identity: 71.27; identified by sequence similarity; putative.
       0.530
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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