Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0868Glutaredoxin-related protein; Similar to PID:840852 percent identity: 68.35; identified by sequence similarity; putative. (221 aa)    
Predicted Functional Partners:
TM_0869
Thioredoxin reductase; Similar to GB:Pyro_h percent identity: 67.62; identified by sequence similarity; putative.
 
 
 0.993
TM_0807
Alkyl hydroperoxide reductase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.936
TM_0866
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 75.26; identified by sequence similarity; putative.
       0.734
TM_0865
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 62.69; identified by sequence similarity; putative.
       0.712
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
       0.694
TM_0864
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58897 PID:1592137 percent identity: 52.03; identified by sequence similarity; putative.
       0.694
TM_0867
Hypothetical protein; Identified by sequence similarity; putative.
       0.694
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
     
  0.591
TM_1828
Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.499
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.493
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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