Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TM_0876Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 57.64; identified by sequence similarity; putative; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (306 aa)    
Predicted Functional Partners:
TM_0875
Hypothetical protein; Identified by sequence similarity; putative.
       0.813
tsaB
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
       0.788
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
  
    0.690
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
       0.644
TM_0878
Pyruvate:ferredoxin 2-oxidoreductase-related protein; Similar to GB:Pyro_h percent identity: 68.24; identified by sequence similarity; putative.
       0.497
TM_0879
Ferredoxin; Identified by sequence similarity; putative.
       0.496
TM_0880
Oxaloacetate decarboxylase, beta subunit; Similar to GB:AE000782 percent identity: 74.01; identified by sequence similarity; putative.
       0.474
TM_0538
Cation efflux system protein; Similar to GB:Pyro_h percent identity: 81.18; identified by sequence similarity; putative; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
 
 
0.463
TM_0882
O-acetylhomoserine sulfhydrylase; Catalyzes the production of homocysteine from O- acetylhomoserine (OAH) and hydrogen sulfide (H2S), a step in the methionine biosynthesis pathway. Is not able to form cystathionine from O-acetylhomoserine and L-cysteine; Belongs to the trans-sulfuration enzymes family.
       0.419
TM_0317
Cation-transporting ATPase, P-type; Similar to GB:AE000782 percent identity: 64.33; identified by sequence similarity; putative.
 
 
 0.414
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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