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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0884Methyltransferase, putative; Similar to PID:1125024 percent identity: 48.92; identified by sequence similarity; putative. (447 aa)    
Predicted Functional Partners:
coaX
Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.825
TM_1863
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 66.67; identified by sequence similarity; putative.
  
     0.773
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. Utilizes a ping-pong kinetic mechanism in which the acetyl group of acetyl-CoA is initially transferred to the enzyme to form an acetyl-enzyme intermediate before subsequent transfer to homoserine to form the final product, O-acetylhomoserine. Has weak activity with succinyl-CoA as the acyl donor. Belongs to the MetA family.
       0.550
TM_0882
O-acetylhomoserine sulfhydrylase; Catalyzes the production of homocysteine from O- acetylhomoserine (OAH) and hydrogen sulfide (H2S), a step in the methionine biosynthesis pathway. Is not able to form cystathionine from O-acetylhomoserine and L-cysteine; Belongs to the trans-sulfuration enzymes family.
       0.550
TM_0482
(R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; Similar to GB:L77117 SP:Q58210 PID:1591496 percent identity: 53.49; identified by sequence similarity; putative.
 
     0.490
TM_1100
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.78; identified by sequence similarity; putative.
  
     0.460
TM_0806
Hypothetical protein; Identified by sequence similarity; putative.
 
    0.445
TM_1367
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 75.00; identified by sequence similarity; putative.
  
     0.443
TM_0880
Oxaloacetate decarboxylase, beta subunit; Similar to GB:AE000782 percent identity: 74.01; identified by sequence similarity; putative.
       0.442
lnt
Acyltransferase, putative; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.
  
     0.438
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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