STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0885Conserved hypothetical protein; Similar to GB:L77117 SP:Q57927 PID:1591207 percent identity: 69.89; identified by sequence similarity; putative. (185 aa)    
Predicted Functional Partners:
TM_0886
Penicillin-binding protein, class 1A; Similar to GP:1763284 percent identity: 55.64; identified by sequence similarity; putative.
       0.810
TM_0887
methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.810
TM_1186
Hypothetical protein; Identified by sequence similarity; putative.
  
     0.615
TM_0034
Iron-sulfur cluster-binding protein; Similar to GP:2622960 percent identity: 62.36; identified by sequence similarity; putative.
  
   
 0.560
TM_0888
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 46.37; identified by sequence similarity; putative.
       0.559
uppP
Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
 
     0.547
dxr
Conserved hypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
       0.465
TM_0890
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 59.04; identified by sequence similarity; putative; Belongs to the peptidase M50B family.
       0.465
ispG
gcpE protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.465
TM_0892
Hypothetical protein; Identified by sequence similarity; putative.
       0.465
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.