STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mazGmazG protein; Catalyzes the hydrolysis of all eight canonical ribonucleoside triphosphates (NTP) and deoxyribonucleoside triphosphates (dNTP) to their corresponding nucleoside monophosphates ((d)NMP) and PPi and subsequently hydrolyzes the resultant PPi to Pi. The NTPase activity with deoxyribonucleoside triphosphates as substrate is higher than corresponding ribonucleoside triphosphates. dGTP is the best substrate among the deoxyribonucleoside triphosphates, and GTP is the best among the ribonucleoside triphosphates. (255 aa)    
Predicted Functional Partners:
TM_0360
mazG-related protein; Similar to GB:L42023 SP:P44723 PID:1003804 PID:1222392 PID:1204710 percent identity: 60.62; identified by sequence similarity; putative.
  
   
 0.863
TM_0912
Basic membrane protein, putative; Similar to GB:AE000783 percent identity: 50.87; identified by sequence similarity; putative.
       0.827
TM_0914
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 55.71; identified by sequence similarity; putative; Belongs to the UPF0111 family.
       0.827
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.826
mtnA
Translation initiation factor, aIF-2B alpha subunit-related; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
       0.825
TM_0910
Flagellar biosynthesis protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
  
    0.822
TM_0916
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 78.52; identified by sequence similarity; putative.
       0.810
flhB
Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
  
    0.797
TM_0906
Conserved hypothetical protein; Similar to PID:1185065 GB:AE000783 percent identity: 58.89; identified by sequence similarity; putative.
  
    0.792
TM_0907
Flagellar biosynthesis protein FlhF; Similar to SP:Q01960 GB:X66445 PID:39919 GB:AL009126 percent identity: 65.48; identified by sequence similarity; putative.
  
    0.789
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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