STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0916Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 78.52; identified by sequence similarity; putative. (284 aa)    
Predicted Functional Partners:
mtnA
Translation initiation factor, aIF-2B alpha subunit-related; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
  
    0.833
TM_0912
Basic membrane protein, putative; Similar to GB:AE000783 percent identity: 50.87; identified by sequence similarity; putative.
     
 0.818
TM_0910
Flagellar biosynthesis protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
       0.810
mazG
mazG protein; Catalyzes the hydrolysis of all eight canonical ribonucleoside triphosphates (NTP) and deoxyribonucleoside triphosphates (dNTP) to their corresponding nucleoside monophosphates ((d)NMP) and PPi and subsequently hydrolyzes the resultant PPi to Pi. The NTPase activity with deoxyribonucleoside triphosphates as substrate is higher than corresponding ribonucleoside triphosphates. dGTP is the best substrate among the deoxyribonucleoside triphosphates, and GTP is the best among the ribonucleoside triphosphates.
       0.810
TM_0914
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 55.71; identified by sequence similarity; putative; Belongs to the UPF0111 family.
       0.810
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.810
TM_0905
Hypothetical protein; Identified by sequence similarity; putative.
  
  
 0.802
TM_0902
RNA polymerase sigma-28 factor, putative; Similar to PID:1419613 percent identity: 61.11; identified by sequence similarity; putative; Belongs to the sigma-70 factor family.
       0.795
cheC
Chemotaxis protein CheC; Involved in restoring normal CheY-P levels by dephosphorylating CheY-P. Inhibits CheD by incorporating in its fold a structural motif that mimics a CheD substrate recognition site to bait and inactivate it; Belongs to the CheC family.
       0.795
TM_0906
Conserved hypothetical protein; Similar to PID:1185065 GB:AE000783 percent identity: 58.89; identified by sequence similarity; putative.
       0.795
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.