STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0935Conserved hypothetical protein; Similar to GB:L77117 SP:Q58821 PID:1592076 percent identity: 53.90; identified by sequence similarity; putative. (145 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.871
mtaD
Conserved hypothetical protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Adenosine-5-monophosphate (AMP) and S-adenosyl-L-methionine (SAM) are not enzyme substrates.
       0.813
TM_0934
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 65.80; identified by sequence similarity; putative.
     
 0.806
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
    
 0.632
TM_0933
Hypothetical protein; Identified by sequence similarity; putative.
       0.574
TM_0715
tRNA nucleotidyl transferase-related protein; Similar to GB:AE000657 percent identity: 56.71; identified by sequence similarity; putative; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
 
 0.539
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
    
  0.537
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.528
TM_1718
Ribulose-phosphate 3-epimerase; Similar to GB:L77117 SP:Q58093 PID:1591395 percent identity: 66.36; identified by sequence similarity; putative; Belongs to the ribulose-phosphate 3-epimerase family.
 
  
 0.504
TM_0756
Galactosyltransferase-related protein; Similar to GP:2198543 percent identity: 61.83; identified by sequence similarity; putative.
  
  
 0.494
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.