STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_0979Conserved hypothetical protein; Similar to SP:P45530 PID:606277 GB:U00096 PID:1789741 percent identity: 56.94; identified by sequence similarity; putative. (87 aa)    
Predicted Functional Partners:
TM_0980
Hypothetical protein; Identified by sequence similarity; putative.
  
 0.998
TM_0981
Conserved hypothetical protein; Similar to PID:1772578 percent identity: 50.00; identified by sequence similarity; putative.
  
 
 0.982
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.907
TM_0982
Conserved hypothetical protein; Similar to SP:P33015 GB:U00009 PID:405956 GB:U00096 PID:1788323 percent identity: 59.56; identified by sequence similarity; putative.
       0.752
TM_0983
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 66.23; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
     
 0.717
TM_0978
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58397 PID:1591652 percent identity: 56.94; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
     
 0.657
ttuA
Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2- thiouridine (m(5)s(2)U or s(2)T). This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (By similarity). Can use free sulfide as sulfur source in vitro. Belongs to the TtcA family. TtuA subfamily.
     
  0.540
TM_0984
Hypothetical protein; Protects the bacterial cell from peptidases.
       0.437
TM_0985
Hypothetical protein; Identified by sequence similarity; putative.
       0.437
TM_0986
Conserved hypothetical protein; Similar to GB:U00096 PID:1788560 percent identity: 54.74; identified by sequence similarity; putative; To E.coli YfaT and P.aeruginosa PA4490.
       0.437
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.