STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_0996Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 72.37; identified by sequence similarity; putative. (80 aa)    
Predicted Functional Partners:
TM_0807
Alkyl hydroperoxide reductase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.962
TM_0997
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58004 PID:1591292 percent identity: 69.30; identified by sequence similarity; putative.
 
  
 0.957
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
  
 
 0.868
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
    
 0.857
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.850
TM_0134
Thioredoxin reductase-related protein; Similar to GB:L04500 PID:388294 SP:P50971 PID:1353197 percent identity: 54.05; identified by sequence similarity; putative.
  
 0.807
TM_0869
Thioredoxin reductase; Similar to GB:Pyro_h percent identity: 67.62; identified by sequence similarity; putative.
  
 0.807
TM_0998
Heavy metal resistance transcriptional regulator; Similar to GB:L10909 SP:P37374 PID:152977 percent identity: 67.53; identified by sequence similarity; putative.
     
 0.784
TM_0308
Alpha-xylosidase; Similar to PID:1881669 percent identity: 63.77; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 31 family.
    
 0.779
TM_0379
NADH oxidase; Similar to GB:AE000782 percent identity: 70.43; identified by sequence similarity; putative.
   
 0.777
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.