close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1006Oxidoreductase, aldo/keto reductase family; Similar to GB:AE000511 PID:2314358 percent identity: 71.74; identified by sequence similarity; putative. (333 aa)    
Predicted Functional Partners:
TM_1005
Transcriptional regulator, putative; Similar to GB:L19201 SP:P09377 GB:X06058 PID:305009 PID:42724 percent identity: 57.24; identified by sequence similarity; putative.
 
     0.738
glpF
Glycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity).
   
 
 0.631
TM_1743
Oxidoreductase, aldo/keto reductase family; Similar to SP:P46905 PID:973332 PID:2415728 GB:AL009126 percent identity: 59.78; identified by sequence similarity; putative.
 
0.556
TM_1009
Oxidoreductase, aldo/keto reductase family; Similar to GB:AL009126 percent identity: 69.23; identified by sequence similarity; putative.
  
0.519
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.