STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1098Hypothetical protein; Identified by sequence similarity; putative. (250 aa)    
Predicted Functional Partners:
TM_1100
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 52.78; identified by sequence similarity; putative.
  
 
  0.823
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
     
 0.793
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.790
TM_1101
Conserved hypothetical protein; Similar to GB:U00096 SP:P76495 PID:1788638 percent identity: 61.35; identified by sequence similarity; putative.
  
    0.787
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. Belongs to the ribonuclease III family.
       0.783
TM_1103
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58536 PID:1591770 percent identity: 54.08; identified by sequence similarity; putative.
       0.783
TM_1104
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 64.00; identified by sequence similarity; putative.
       0.783
TM_1105
NADH dehydrogenase, putative; Similar to PID:1652329 percent identity: 60.22; identified by sequence similarity; putative.
       0.783
TM_1106
Hypothetical protein; Identified by sequence similarity; putative.
       0.783
TM_1107
Conserved hypothetical protein; Similar to PID:1652333 percent identity: 54.67; identified by sequence similarity; putative.
       0.783
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.