STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1119Hypothetical protein; Identified by sequence similarity; putative. (349 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.782
sigA
RNA polymerase sigma-A factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.779
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.775
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.775
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
    
 
 0.524
TM_1120
Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein; Similar to SP:P10904 GB:U00039 GB:M33735 PID:43244 PID:466589 percent identity: 51.42; identified by sequence similarity; putative.
  
    0.482
TM_1121
Glycerol-3-phosphate ABC transporter, permease protein; Similar to SP:P10905 GB:U00039 PID:43247 PID:466588 GB:U00096 percent identity: 61.32; identified by sequence similarity; putative.
       0.469
TM_1122
Glycerol-3-phosphate ABC transporter, permease protein; Similar to SP:P10906 GB:U00039 PID:43248 PID:466587 GB:U00096 percent identity: 59.48; identified by sequence similarity; putative.
       0.452
TM_0930
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58222 PID:1591501 percent identity: 48.77; identified by sequence similarity; putative.
  
    0.408
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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