Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_1140Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 62.41; identified by sequence similarity; putative. (215 aa)    
Predicted Functional Partners:
TM_1138
Branched chain amino acid ABC transporter, ATP-binding protein; Similar to GB:D12589 SP:P30293 GB:X52093 PID:217074 percent identity: 74.02; identified by sequence similarity; putative.
 
    0.875
TM_1137
Branched chain amino acid ABC transporter, permease protein; Similar to GB:D90223 SP:P21628 GB:M64046 PID:216865 percent identity: 62.72; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
  
    0.860
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 0.848
TM_1139
Branched chain amino acid ABC transporter, ATP-binding protein; Similar to GB:AE000782 percent identity: 74.48; identified by sequence similarity; putative.
 
    0.844
TM_1136
Branched chain amino acid ABC transporter, permease protein; Similar to GB:D12589 SP:P30295 GB:X52093 PID:217072 percent identity: 68.09; identified by sequence similarity; putative; Belongs to the binding-protein-dependent transport system permease family.
 
    0.841
pyk
Pyruvate kinase; Similar to GB:AL009126 percent identity: 64.53; identified by sequence similarity; putative; Belongs to the pyruvate kinase family.
   
 
 0.785
rpsB
Ribosomal protein S2; Similar to GB:AL009126 percent identity: 81.40; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
   
   0.776
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.775
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. Belongs to the universal ribosomal protein uS4 family.
   
 
 0.773
rpsC
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
    
 
 0.767
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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