Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_1170ABC transporter, periplasmic substrate-binding protein/conserved hypothetical protein; Similar to GB:U00096 SP:P39174 PID:1736579 PID:1736587 PID:1788228 percent identity: 46.34; identified by sequence similarity; putative. (618 aa)    
Predicted Functional Partners:
TM_1788
Conserved hypothetical protein, GGDEF domain; Similar to GB:AE000657 percent identity: 60.13; identified by sequence similarity; putative.
 
 0.867
TM_0972
Conserved hypothetical protein, GGDEF domain; Similar to GB:AE000657 percent identity: 63.80; identified by sequence similarity; putative.
 
 0.835
TM_1169
3-oxoacyl-(acyl carrier protein) reductase; Similar to GB:AE000657 percent identity: 61.70; identified by sequence similarity; putative.
   
 
 0.826
TM_1184
pleD-related protein; Similar to PID:1652841 percent identity: 50.78; identified by sequence similarity; putative.
 
 0.791
TM_1171
Transcriptional regulator, crp family; Similar to GB:Z26044 SP:P47200 PID:398391 percent identity: 50.56; identified by sequence similarity; putative.
     
 0.787
TM_0155
Chorismate mutase/prephenate dehydratase; Similar to GB:AE000782 percent identity: 80.45; identified by sequence similarity; putative.
    
 0.770
TM_0842
Response regulator; Similar to PID:1651932 percent identity: 56.68; identified by sequence similarity; putative.
  
 
 0.606
hcp
Prismane protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
    
  0.600
TM_0143
Response regulator; Similar to PID:1651878 percent identity: 53.02; identified by sequence similarity; putative.
  
 0.591
TM_0592
Amino acid ABC transporter, permease protein; Similar to GB:AE000782 percent identity: 72.86; identified by sequence similarity; putative.
  
 0.585
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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