Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_1171Transcriptional regulator, crp family; Similar to GB:Z26044 SP:P47200 PID:398391 percent identity: 50.56; identified by sequence similarity; putative. (201 aa)    
Predicted Functional Partners:
sigA
RNA polymerase sigma-A factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.873
pyrBI
Aspartate carbamoyltransferase, catalytic and regulatory chains; Similar to PID:1772605 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; In the N-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.873
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.870
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.861
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.858
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
    
 
 0.842
TM_1169
3-oxoacyl-(acyl carrier protein) reductase; Similar to GB:AE000657 percent identity: 61.70; identified by sequence similarity; putative.
  
 0.813
glpF
Glycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity).
   
 0.801
TM_0038
6-pyruvoyl tetrahydrobiopterin synthase, putative; Similar to PID:882658 GB:U00096 SP:Q46903 PID:1789124 percent identity: 62.18; identified by sequence similarity; putative.
   
  0.792
TM_1170
ABC transporter, periplasmic substrate-binding protein/conserved hypothetical protein; Similar to GB:U00096 SP:P39174 PID:1736579 PID:1736587 PID:1788228 percent identity: 46.34; identified by sequence similarity; putative.
     
 0.787
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.