Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
hcpPrismane protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (431 aa)    
Predicted Functional Partners:
gdhA
Glutamate dehydrogenase; Similar to PID:1743418 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.959
glnA
Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under [...]
     
 0.957
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
   
 0.933
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
    
 0.824
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
     
 0.744
TM_0395
NADH oxidase, putative; Similar to GB:AE000782 percent identity: 66.19; identified by sequence similarity; putative.
  
 
 0.705
TM_0754
Oxidoreductase; Similar to GB:Pyro_h percent identity: 63.41; identified by sequence similarity; putative.
  
 
 0.705
TM_1171
Transcriptional regulator, crp family; Similar to GB:Z26044 SP:P47200 PID:398391 percent identity: 50.56; identified by sequence similarity; putative.
     
 0.668
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
    
 0.656
TM_0201
NADP-reducing hydrogenase, subunit D, putative; Similar to GB:U07229 PID:466366 percent identity: 69.31; identified by sequence similarity; putative.
    
 0.603
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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