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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1184pleD-related protein; Similar to PID:1652841 percent identity: 50.78; identified by sequence similarity; putative. (643 aa)    
Predicted Functional Partners:
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
   
 0.998
TM_0143
Response regulator; Similar to PID:1651878 percent identity: 53.02; identified by sequence similarity; putative.
 
0.917
TM_1147
Conserved hypothetical protein; Similar to PID:558266 percent identity: 58.48; identified by sequence similarity; putative.
 0.862
TM_1830
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 71.11; identified by sequence similarity; putative.
 
 
 0.857
TM_1170
ABC transporter, periplasmic substrate-binding protein/conserved hypothetical protein; Similar to GB:U00096 SP:P39174 PID:1736579 PID:1736587 PID:1788228 percent identity: 46.34; identified by sequence similarity; putative.
 0.847
TM_0186
Response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP. Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'- phosphoguanylyl(3'->5')guanosine (pGpG).
 0.845
TM_1183
Oxidoreductase, aldo/keto reductase family; Similar to GB:AE000666 percent identity: 61.05; identified by sequence similarity; putative.
  
    0.812
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
       0.810
TM_0842
Response regulator; Similar to PID:1651932 percent identity: 56.68; identified by sequence similarity; putative.
 
 0.799
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 
 0.789
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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