STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (166 aa)    
Predicted Functional Partners:
gldA
Glycerol dehydrogenase; Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions (By similarity). Belongs to the iron-containing alcohol dehydrogenase family.
     
 0.992
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
     
 0.931
TM_0715
tRNA nucleotidyl transferase-related protein; Similar to GB:AE000657 percent identity: 56.71; identified by sequence similarity; putative; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.811
TM_1183
Oxidoreductase, aldo/keto reductase family; Similar to GB:AE000666 percent identity: 61.05; identified by sequence similarity; putative.
       0.810
TM_1184
pleD-related protein; Similar to PID:1652841 percent identity: 50.78; identified by sequence similarity; putative.
       0.810
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (Probable). Uses NADPH as a reductant with much more efficiency than NADH; Belongs to the DapB family.
  
    0.743
coaE
Conserved hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
    0.658
pyrBI
Aspartate carbamoyltransferase, catalytic and regulatory chains; Similar to PID:1772605 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; In the N-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
    
 0.647
TM_1180
Hypothetical protein; Identified by sequence similarity; putative.
       0.574
TM_1181
Conserved hypothetical protein; Similar to SP:P54570 PID:1303984 GB:AL009126 percent identity: 71.93; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family.
       0.574
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.