STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacZBeta-galactosidase; Similar to GB:U08186 PID:473272 GB:AE000512 percent identity: 99.61; identified by sequence similarity; putative. (1087 aa)    
Predicted Functional Partners:
galA
Alpha-galactosidase; Hydrolyzes the short-chain alpha-galactosaccharides raffinose, melibiose and stachyose.
 
 
 0.996
TM_1195
Beta-galactosidase; Similar to GB:U08186 PID:473271 percent identity: 99.53; identified by sequence similarity; putative.
   
 0.995
TM_0310
beta-D-galactosidase; Similar to GB:L03424 PID:551691 percent identity: 68.26; identified by sequence similarity; putative.
   
 0.986
TM_0282
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 
 
 0.984
glk
Glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. Can also phosphorylate 2- deoxyglucose, with lower efficiency. ITP can also serve as a phosphoryl donor.
     
 0.977
aglA
Alpha-glucosidase; Alpha-glycosidase with a very broad specificity. Hydrolyzes maltose and other small maltooligosaccharides but is inactive against the polymeric substrate starch. AglA is not specific with respect to the configuration at the C-4 position of its substrates because glycosidic derivatives of D-galactose are also hydrolyzed. Does not cleave beta-glycosidic bonds.
    
  0.977
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
 
 0.922
xylA
Xylose isomerase; Similar to SP:P45687 PID:625180 percent identity: 71.21; identified by sequence similarity; putative; Belongs to the xylose isomerase family.
    
 0.888
galT
Galactose-1-phosphate uridylyltransferase; Similar to GP:2660643 percent identity: 100.00; identified by sequence similarity; putative.
       0.781
TM_1194
Oligopeptide ABC transporter, ATP-binding protein; Similar to GB:U08186 PID:473270 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
       0.773
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.