| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NADK | TM_0703 | TM_1733 | TM_0703 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | 0.428 |
| NADK | cobB | TM_1733 | TM_0490 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear. | 0.992 |
| NADK | nadD | TM_1733 | TM_0097 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.995 |
| NADK | nadE1 | TM_1733 | TM_0645 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | NH(3)-dependent NAD(+) synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.994 |
| NADK | nadE2 | TM_1733 | TM_1253 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.998 |
| TM_0703 | NADK | TM_0703 | TM_1733 | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | 0.428 |
| TM_0703 | cobB | TM_0703 | TM_0490 | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear. | 0.574 |
| TM_0703 | nadD | TM_0703 | TM_0097 | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.998 |
| TM_0703 | nadE1 | TM_0703 | TM_0645 | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | NH(3)-dependent NAD(+) synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.565 |
| TM_0703 | nadE2 | TM_0703 | TM_1253 | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.844 |
| TM_1217 | nadE2 | TM_1217 | TM_1253 | Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.938 |
| TM_1217 | purF | TM_1217 | TM_1247 | Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.997 |
| TM_1217 | purH | TM_1217 | TM_1249 | Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Similar to GB:AE000657 percent identity: 61.39; identified by sequence similarity; putative. | 0.480 |
| cobB | NADK | TM_0490 | TM_1733 | Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear. | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | 0.992 |
| cobB | TM_0703 | TM_0490 | TM_0703 | Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear. | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | 0.574 |
| cobB | nadD | TM_0490 | TM_0097 | Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear. | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.995 |
| cobB | nadE1 | TM_0490 | TM_0645 | Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear. | NH(3)-dependent NAD(+) synthetase, putative; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.992 |
| cobB | nadE2 | TM_0490 | TM_1253 | Regulatory protein, SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP- ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.998 |
| nadD | NADK | TM_0097 | TM_1733 | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Conserved hypothetical protein; Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP (By similarity). | 0.995 |
| nadD | TM_0703 | TM_0097 | TM_0703 | Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family. | 0.998 |