STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1259Phosphate regulon transcriptional regulatory protein PhoB; Similar to GB:M31793 SP:P45606 PID:152773 percent identity: 63.64; identified by sequence similarity; putative. (229 aa)    
Predicted Functional Partners:
TM_1258
Sensor histidine kinase, PhoR-related; Similar to GB:M23549 SP:P23545 PID:143331 PID:2293271 GB:AL009126 percent identity: 56.96; identified by sequence similarity; putative.
 
 0.987
TM_1654
Sensor histidine kinase HpkA; Similar to PID:1575578 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative.
 0.901
TM_0853
Sensor histidine kinase; Similar to PID:1575578 GB:AE000512 percent identity: 61.11; identified by sequence similarity; putative.
 0.878
TM_0400
Sensor histidine kinase; Similar to PID:1001613 PID:1001628 percent identity: 54.23; identified by sequence similarity; putative.
 0.876
phoU1
Phosphate transport system regulator PhoU; Plays a role in the regulation of phosphate uptake.
  
  
 0.822
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
  
 0.785
TM_1262
Phosphate ABC transporter, permease protein; Similar to GB:AE000666 percent identity: 59.61; identified by sequence similarity; putative.
     
 0.782
TM_1263
Phosphate ABC transporter, permease protein; Similar to GB:AE000666 percent identity: 60.15; identified by sequence similarity; putative.
     
 0.782
TM_1359
Sensor histidine kinase; Similar to GB:L13078 SP:Q06067 PID:290419 GB:U00096 PID:1736874 percent identity: 56.58; identified by sequence similarity; putative.
  
  
 0.699
TM_0127
Sensor histidine kinase; Similar to PID:2352098 percent identity: 54.13; identified by sequence similarity; putative.
 
 0.687
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.