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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtcBConserved hypothetical protein; Similar to GB:AE000782 percent identity: 71.73; identified by sequence similarity; putative; Belongs to the RtcB family. (474 aa)    
Predicted Functional Partners:
TM_1083
Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity). May also act as a chaperone or modulator of proteins involved in DNA or RNA processing.
  
 0.790
gltX1
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
     0.759
TM_1354
Inosine-5-monophosphate dehydrogenase-related protein; Similar to GB:L77117 SP:Q59011 PID:1592337 percent identity: 60.27; identified by sequence similarity; putative.
       0.749
TM_1356
Hypothetical protein; Identified by sequence similarity; putative.
       0.741
TM_1350
Lipase, putative; Similar to GB:AE000782 percent identity: 62.55; identified by sequence similarity; putative.
       0.730
TM_1348
Hypothetical protein; Identified by sequence similarity; putative.
       0.726
TM_1349
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 56.41; identified by sequence similarity; putative.
       0.726
TM_1352
Hypothetical protein; Identified by sequence similarity; putative.
       0.726
TM_1353
Hypothetical protein; Identified by sequence similarity; putative.
       0.726
TM_1355
Hypothetical protein; Identified by sequence similarity; putative.
       0.726
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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