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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1362Motility protein PilT; Similar to GB:AE000657 percent identity: 66.67; identified by sequence similarity; putative. (360 aa)    
Predicted Functional Partners:
TM_0094
General secretion pathway protein F, putative; Similar to GB:AE000657 percent identity: 58.04; identified by sequence similarity; putative.
  
 0.865
TM_1696
Type IV prepilin peptidase; Similar to GB:AE000657 percent identity: 61.90; identified by sequence similarity; putative.
 
   
 0.861
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
     
 0.836
prfA
Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.790
TM_1359
Sensor histidine kinase; Similar to GB:L13078 SP:Q06067 PID:290419 GB:U00096 PID:1736874 percent identity: 56.58; identified by sequence similarity; putative.
  
    0.786
TM_1360
Response regulator; Similar to GB:L09228 SP:P35163 PID:410141 GB:AL009126 percent identity: 65.79; identified by sequence similarity; putative.
     
 0.764
fliE
Flagellar hook-basal body complex protein FliE; Similar to GB:M54965 SP:P24502 PID:142917 GB:AL009126 percent identity: 66.67; identified by sequence similarity; putative.
     
 0.749
TM_0088
comE protein, putative; Similar to SP:P31772 GB:L42023 PID:1003754 PID:1222365 PID:148874 percent identity: 65.23; identified by sequence similarity; putative; Belongs to the bacterial secretin family.
 
   
 0.741
TM_1364
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
     
 0.734
TM_1365
Flagellar basal-body rod protein FlgC; Similar to PID:1165277 PID:1196316 SP:Q57466 GB:AE000783 percent identity: 72.46; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
     
 0.734
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.