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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1419Myo-inositol-1-phosphate synthase-related protein; Similar to GB:AE000782 percent identity: 50.86; identified by sequence similarity; putative. (382 aa)    
Predicted Functional Partners:
suhB
Inositol monophosphatase family protein, putative; Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P) but displaying a 20-fold higher rate of hydrolysis of D-I-1-P than of the L isomer, 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6- phosphate, fructose-6-phosphate, 5'-AMP and NAD(+). May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.
  
 
 0.997
TM_0987
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 78.97; identified by sequence similarity; putative.
  
     0.731
TM_0988
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 69.40; identified by sequence similarity; putative.
  
     0.712
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
  
     0.578
TM_0370
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 92.41; identified by sequence similarity; putative; Belongs to the UPF0273 family.
  
     0.552
rex2
Conserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
 
     0.514
TM_1011
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 66.29; identified by sequence similarity; putative.
  
     0.511
TM_0990
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 71.88; identified by sequence similarity; putative.
  
 
 
 0.509
TM_1861
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Similar to SP:P46322 PID:893358 PID:1842439 GB:AL009126 percent identity: 60.87; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.498
TM_0032
Transcriptional regulator, XylR-related; Similar to PID:1208894 SP:Q44406 percent identity: 51.23; identified by sequence similarity; putative.
    
  0.488
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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