Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TM_1419Myo-inositol-1-phosphate synthase-related protein; Similar to GB:AE000782 percent identity: 50.86; identified by sequence similarity; putative. (382 aa)    
Predicted Functional Partners:
suhB
Inositol monophosphatase family protein, putative; Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, both D and L isomers of inositol-1-phosphate (I-1-P) but displaying a 20-fold higher rate of hydrolysis of D-I-1-P than of the L isomer, 2'-AMP, pNPP, inositol-2-phosphate, beta-glycerol phosphate, and alpha-D-glucose-1-phosphate. Cannot hydrolyze glucose-6- phosphate, fructose-6-phosphate, 5'-AMP and NAD(+). May be involved in the biosynthesis of a unique osmolyte, di-myo-inositol 1,1-phosphate.
  
 
 0.980
glk
Glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. Can also phosphorylate 2- deoxyglucose, with lower efficiency. ITP can also serve as a phosphoryl donor.
     
  0.954
TM_0987
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 78.97; identified by sequence similarity; putative.
  
     0.731
TM_0988
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 69.40; identified by sequence similarity; putative.
  
     0.712
TM_0990
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 71.88; identified by sequence similarity; putative.
  
 
 
 0.595
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
  
     0.578
TM_0370
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 92.41; identified by sequence similarity; putative; Belongs to the UPF0273 family.
  
     0.552
rex2
Conserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
 
     0.514
TM_1011
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 66.29; identified by sequence similarity; putative.
  
     0.511
TM_1420
Hypothetical protein; Might be part of a multi-protein complex, possibly involved in metal cluster assembly.
       0.448
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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