Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TM_1421Hydrogenase, putative; Similar to GB:X57838 PID:40828 percent identity: 52.17; identified by sequence similarity; putative. (301 aa)    
Predicted Functional Partners:
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
   
 0.997
TM_1422
rnfB-related protein; Similar to PID:871466 percent identity: 56.34; identified by sequence similarity; putative.
     0.994
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
   
 0.990
TM_0228
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 72.27; identified by sequence similarity; putative.
   
 0.962
TM_1420
Hypothetical protein; Might be part of a multi-protein complex, possibly involved in metal cluster assembly.
 
 0.955
TM_1423
Hypothetical protein; Identified by sequence similarity; putative.
 
     0.948
TM_1426
Fe-hydrogenase, subunit alpha; Similar to GP:2865517 percent identity: 100.00; identified by sequence similarity; putative.
 
 
0.880
TM_1424
Fe-hydrogenase, subunit gamma; Similar to GP:2865515 percent identity: 100.00; identified by sequence similarity; putative.
  
 0.858
rex2
Conserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.754
TM_1289
Ferredoxin; Similar to SP:P00211 percent identity: 66.00; identified by sequence similarity; putative.
 
 
 0.692
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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