close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1421Hydrogenase, putative; Similar to GB:X57838 PID:40828 percent identity: 52.17; identified by sequence similarity; putative. (301 aa)    
Predicted Functional Partners:
TM_1422
rnfB-related protein; Similar to PID:871466 percent identity: 56.34; identified by sequence similarity; putative.
     0.994
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
    
 0.965
TM_1423
Hypothetical protein; Identified by sequence similarity; putative.
 
     0.948
TM_1420
Hypothetical protein; Might be part of a multi-protein complex, possibly involved in metal cluster assembly.
 
 
 0.943
TM_1426
Fe-hydrogenase, subunit alpha; Similar to GP:2865517 percent identity: 100.00; identified by sequence similarity; putative.
 
 
0.892
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
    
 0.838
TM_1424
Fe-hydrogenase, subunit gamma; Similar to GP:2865515 percent identity: 100.00; identified by sequence similarity; putative.
  
 
 0.819
rex2
Conserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.754
TM_0201
NADP-reducing hydrogenase, subunit D, putative; Similar to GB:U07229 PID:466366 percent identity: 69.31; identified by sequence similarity; putative.
 
 
0.700
TM_0445
Conserved hypothetical protein; Similar to PID:1001414 PID:1001399 percent identity: 52.55; identified by sequence similarity; putative.
 
     0.670
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.