STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glpFGlycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity). (234 aa)    
Predicted Functional Partners:
glpK2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
 
 0.946
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
    
 
 0.865
glpK1
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.825
TM_1431
Glycerol uptake operon antiterminator; Similar to GB:M99611 SP:P30300 PID:142996 PID:2226135 GB:AL009126 percent identity: 61.14; identified by sequence similarity; putative.
 
  
 0.820
TM_1171
Transcriptional regulator, crp family; Similar to GB:Z26044 SP:P47200 PID:398391 percent identity: 50.56; identified by sequence similarity; putative.
   
 0.801
TM_1695
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 53.37; identified by sequence similarity; putative.
    
 
 0.758
TM_1773
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58741 PID:1591987 percent identity: 54.39; identified by sequence similarity; putative.
    
 
 0.758
TM_0612
Hypothetical protein; Identified by sequence similarity; putative.
    
   0.746
TM_1846
Beta transducin-related protein; Similar to PID:607003 percent identity: 49.46; identified by sequence similarity; putative.
    
   0.746
TM_1432
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 54.61; identified by sequence similarity; putative.
     
 0.686
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.