Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_1435Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 62.39; identified by sequence similarity; putative. (131 aa)    
Predicted Functional Partners:
TM_0268
5-methyltetrahydrofolate S-homocysteine methyltransferase; Similar to GB:U00017 PID:466997 percent identity: 54.29; identified by sequence similarity; putative.
    
  0.871
TM_1432
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 54.61; identified by sequence similarity; putative.
       0.817
TM_1434
Hypothetical protein; Identified by sequence similarity; putative.
       0.813
TM_1433
Oxidoreductase, putative; Similar to GB:AE000782 percent identity: 56.65; identified by sequence similarity; putative.
       0.781
glpK2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
       0.575
TM_1431
Glycerol uptake operon antiterminator; Similar to GB:M99611 SP:P30300 PID:142996 PID:2226135 GB:AL009126 percent identity: 61.14; identified by sequence similarity; putative.
       0.575
TM_0122
Ferric uptake regulation protein; Similar to PID:511113 percent identity: 57.14; identified by sequence similarity; putative; Belongs to the Fur family.
  
    0.529
TM_1515
Ferric uptake regulation protein; Similar to PID:1652859 percent identity: 59.70; identified by sequence similarity; putative; Belongs to the Fur family.
  
    0.529
TM_1776
Ferric uptake regulation protein; Similar to GB:L11361 PID:349012 percent identity: 56.52; identified by sequence similarity; putative; Belongs to the Fur family.
  
    0.529
glpF
Glycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane (By similarity).
       0.484
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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