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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1442Anti-sigma factor antagonist, putative; In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition; Belongs to the anti-sigma-factor antagonist family. (110 aa)    
Predicted Functional Partners:
TM_0733
sigma-B regulator, putative; Similar to GP:2660754 percent identity: 49.59; identified by sequence similarity; putative.
 
 0.977
TM_0467
Regulatory protein, putative; Similar to PID:1653310 percent identity: 53.02; identified by sequence similarity; putative.
 
 0.941
TM_1354
Inosine-5-monophosphate dehydrogenase-related protein; Similar to GB:L77117 SP:Q59011 PID:1592337 percent identity: 60.27; identified by sequence similarity; putative.
  
 0.939
TM_1440
Translation initiation factor, eIF-2B alpha subunit-related; Similar to SP:Q64270 PID:1050328 PID:623033 percent identity: 53.03; identified by sequence similarity; putative; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
     0.833
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.811
cmk
Cytidylate kinase; Similar to SP:P38493 GB:U11687 PID:533105 PID:1146214 GB:AL009126 percent identity: 68.18; identified by sequence similarity; putative.
       0.811
ispH
lytB protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.811
TM_1423
Hypothetical protein; Identified by sequence similarity; putative.
  
 0.756
TM_1267
thiH protein, putative; Similar to SP:P30140 PID:396329 PID:414236 GB:U00096 PID:1790423 percent identity: 53.87; identified by sequence similarity; putative.
  
    0.747
flgH
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
   
    0.726
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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