STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glkGlucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. Can also phosphorylate 2- deoxyglucose, with lower efficiency. ITP can also serve as a phosphoryl donor. (317 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Similar to GB:L77117 PID:1500502 percent identity: 61.52; identified by sequence similarity; putative.
 
 
 0.993
TM_0282
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
    
 0.991
lacZ
Beta-galactosidase; Similar to GB:U08186 PID:473272 GB:AE000512 percent identity: 99.61; identified by sequence similarity; putative.
     
 0.977
tal
Transaldolase-related protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Does not show fructose-6-P aldolase activity; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.933
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.932
xylA
Xylose isomerase; Similar to SP:P45687 PID:625180 percent identity: 71.21; identified by sequence similarity; putative; Belongs to the xylose isomerase family.
    
 0.931
TM_0273
Fructose-bisphosphate aldolase; Similar to GB:AE000657 percent identity: 78.33; identified by sequence similarity; putative.
    
 0.930
TM_1762
Transketolase, putative; Similar to GP:452486 percent identity: 53.52; identified by sequence similarity; putative.
  
 
 0.930
TM_1585
Glycerate kinase, putative; Involved in the degradation of serine via 3-hydroxypyruvate. Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2- phosphoglycerate.
    
  0.927
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
    
  0.926
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.