STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glkGlucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. Can also phosphorylate 2- deoxyglucose, with lower efficiency. ITP can also serve as a phosphoryl donor. (317 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Similar to GB:L77117 PID:1500502 percent identity: 61.52; identified by sequence similarity; putative.
 
  
 0.964
TM_0282
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
    
 0.956
bglT
6-phospho-beta-glucosidase; Hydrolyzes cellobiose 6'-phosphate into glucose 6-phosphate (Glc6P) and glucose.
     
  0.954
TM_1419
Myo-inositol-1-phosphate synthase-related protein; Similar to GB:AE000782 percent identity: 50.86; identified by sequence similarity; putative.
     
  0.954
lacZ
Beta-galactosidase; Similar to GB:U08186 PID:473272 GB:AE000512 percent identity: 99.61; identified by sequence similarity; putative.
     
 0.939
TM_0736
Mannose-6-phosphate isomerase; Similar to GB:U02562 SP:P39841 PID:1129073 PID:476092 GB:AL009126 percent identity: 56.25; identified by sequence similarity; putative.
 
 
 0.909
xylA
Xylose isomerase; Similar to SP:P45687 PID:625180 percent identity: 71.21; identified by sequence similarity; putative; Belongs to the xylose isomerase family.
    
 0.901
tal
Transaldolase-related protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Does not show fructose-6-P aldolase activity; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.887
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.884
TM_0273
Fructose-bisphosphate aldolase; Similar to GB:AE000657 percent identity: 78.33; identified by sequence similarity; putative.
    
 0.883
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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