STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmcALConserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (418 aa)    
Predicted Functional Partners:
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
    0.742
TM_1514
Hypothetical protein; Identified by sequence similarity; putative.
       0.732
TM_1515
Ferric uptake regulation protein; Similar to PID:1652859 percent identity: 59.70; identified by sequence similarity; putative; Belongs to the Fur family.
       0.732
TM_0691
Conserved hypothetical protein; Similar to GP:2983274 percent identity: 53.77; identified by sequence similarity; putative.
  
     0.718
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (Probable). Uses NADPH as a reductant with much more efficiency than NADH; Belongs to the DapB family.
 
     0.716
TM_1516
Hydrolase, ama/hipO/hyuC family; Similar to GB:AL009126 percent identity: 57.63; identified by sequence similarity; putative.
       0.707
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.707
TM_1518
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 64.96; identified by sequence similarity; putative; Belongs to the aspartokinase family.
       0.707
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
       0.682
dapH
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase-related protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
       0.678
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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