STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dapH2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase-related protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (236 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (Probable). Uses NADPH as a reductant with much more efficiency than NADH; Belongs to the DapB family.
 
 
 0.997
TM_1523
Aspartate-semialdehyde dehydrogenase; Similar to GB:AE000657 percent identity: 69.47; identified by sequence similarity; putative; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 0.977
TM_1516
Hydrolase, ama/hipO/hyuC family; Similar to GB:AL009126 percent identity: 57.63; identified by sequence similarity; putative.
 
  
 0.957
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.942
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. Also catalyzes the racemization of certain amino acids, including Lys, with low efficiency. Belongs to the diaminopimelate epimerase family.
 
  
 0.918
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
  
 0.874
TM_1518
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 64.96; identified by sequence similarity; putative; Belongs to the aspartokinase family.
 
  
 0.850
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.738
TM_1515
Ferric uptake regulation protein; Similar to PID:1652859 percent identity: 59.70; identified by sequence similarity; putative; Belongs to the Fur family.
     
 0.722
TM_1514
Hypothetical protein; Identified by sequence similarity; putative.
       0.716
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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