STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1545Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (218 aa)    
Predicted Functional Partners:
TM_1546
Single stranded DNA-specific exonuclease, putative; Similar to GB:AL009126 percent identity: 59.14; identified by sequence similarity; putative.
     
 0.824
TM_0606
Hypothetical protein; Identified by sequence similarity; putative.
  
    0.739
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.618
TM_0706
Hypothetical protein; Identified by sequence similarity; putative.
 
    0.596
TM_1548
Lipopolysaccharide biosynthesis protein; Similar to GP:1773343 percent identity: 61.19; identified by sequence similarity; putative.
       0.580
TM_1547
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 58.04; identified by sequence similarity; putative.
  
    0.578
wecA
Methicillin resistance protein; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55), the lipid intermediate involved in the synthesis of various bacterial cell envelope components. The enzyme is highly active when tested with C35- P, instead of its natural C55-P lipid substrate, suggesting that at least a 35-carbon chain is required for the lipid to be a substrate of WecA; Belongs to the glycosyltransferase 4 family. WecA subfamily.
       0.570
miaA
tRNA delta-2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
  
    0.561
TM_1075
Hypothetical protein; Identified by sequence similarity; putative.
  
     0.561
TM_0914
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 55.71; identified by sequence similarity; putative; Belongs to the UPF0111 family.
 
     0.508
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.