STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1552Pyruvate formate-lyase activating enzyme, putative; Similar to GB:AE000782 percent identity: 68.04; identified by sequence similarity; putative. (331 aa)    
Predicted Functional Partners:
TM_0087
Conserved hypothetical protein; Similar to PID:1707828 percent identity: 65.23; identified by sequence similarity; putative; Belongs to the MEMO1 family.
     0.973
TM_1551
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 61.99; identified by sequence similarity; putative.
 
     0.954
TM_1553
Conserved hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
       0.810
TM_1556
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
 0.707
TM_1557
DNA repair protein; Similar to SP:Q02170 percent identity: 66.82; identified by sequence similarity; putative; Belongs to the UPF0758 family.
       0.703
TM_1554
Hypothetical protein; Identified by sequence similarity; putative.
  
    0.685
TM_1558
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 62.64; identified by sequence similarity; putative.
       0.683
TM_1555
Hypothetical protein; Identified by sequence similarity; putative.
       0.672
TM_1560
Serine cycle enzyme, putative; Similar to PID:694120 SP:Q49135 percent identity: 55.32; identified by sequence similarity; putative.
       0.661
tgt
tRNA guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
       0.661
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.