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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1588Conserved hypothetical protein, GGDEF domain; Similar to GB:AE000657 percent identity: 57.07; identified by sequence similarity; putative. (240 aa)    
Predicted Functional Partners:
TM_1587
Hypothetical protein; Identified by sequence similarity; putative.
   
   0.794
TM_1830
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 71.11; identified by sequence similarity; putative.
  
     0.774
TM_1678
Conserved hypothetical protein; Similar to PID:558266 percent identity: 65.15; identified by sequence similarity; putative.
 
  0.646
TM_0186
Response regulator; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP. Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'- phosphoguanylyl(3'->5')guanosine (pGpG).
 
 
  0.639
TM_1467
Conserved hypothetical protein; Similar to PID:558266 percent identity: 64.17; identified by sequence similarity; putative.
 
  0.625
TM_1170
ABC transporter, periplasmic substrate-binding protein/conserved hypothetical protein; Similar to GB:U00096 SP:P39174 PID:1736579 PID:1736587 PID:1788228 percent identity: 46.34; identified by sequence similarity; putative.
 0.610
TM_1147
Conserved hypothetical protein; Similar to PID:558266 percent identity: 58.48; identified by sequence similarity; putative.
 
 
  0.579
TM_1585
Glycerate kinase, putative; Involved in the degradation of serine via 3-hydroxypyruvate. Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2- phosphoglycerate.
       0.568
TM_1586
Hypothetical protein; Identified by sequence similarity; putative.
       0.568
TM_0854
Hypothetical protein; Identified by sequence similarity; putative.
 
   
  0.566
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.