STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1595Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 58.22; identified by sequence similarity; putative. (333 aa)    
Predicted Functional Partners:
TM_1594
Conserved hypothetical protein, GGDEF domain; Similar to GB:AE000657 percent identity: 60.77; identified by sequence similarity; putative.
       0.810
TM_1596
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
       0.795
truB
tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.641
rbfA
Ribosome binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.581
TM_1597
Hypothetical protein; Catalyzes the interconversion of D-lysine and L-lysine. Has also high activity toward ornithine, and weaker activity toward alanine. Contributes to production of D-lysine and D-alanine for use as peptidoglycan components.
       0.567
TM_1601
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 62.14; identified by sequence similarity; putative.
       0.512
TM_1598
RNA polymerase sigma-E factor; Similar to SP:P34086 PID:1045628 PID:987648 GB:U00096 PID:1788926 percent identity: 61.67; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. ECF subfamily.
       0.488
TM_1599
Hypothetical protein; Identified by sequence similarity; putative.
       0.488
TM_1600
Hypothetical protein; Identified by sequence similarity; putative.
       0.488
niaR
Transcriptional regulator, biotin repressor family; Probably functions to regulate transcription of NAD metabolic genes. Binds to DNA upstream of the probable nadBII/nadA/nadC and niaRP operons in a nicotinic acid dependent fashion. Nicotinic acid may be a corepressor.
       0.467
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.