STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1603Permease, putative; Similar to GB:AL009126 percent identity: 59.95; identified by sequence similarity; putative. (422 aa)    
Predicted Functional Partners:
niaR
Transcriptional regulator, biotin repressor family; Probably functions to regulate transcription of NAD metabolic genes. Binds to DNA upstream of the probable nadBII/nadA/nadC and niaRP operons in a nicotinic acid dependent fashion. Nicotinic acid may be a corepressor.
 
   
 0.907
TM_1598
RNA polymerase sigma-E factor; Similar to SP:P34086 PID:1045628 PID:987648 GB:U00096 PID:1788926 percent identity: 61.67; identified by sequence similarity; putative; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.764
TM_1599
Hypothetical protein; Identified by sequence similarity; putative.
       0.747
TM_1600
Hypothetical protein; Identified by sequence similarity; putative.
       0.747
TM_1601
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 62.14; identified by sequence similarity; putative.
       0.747
TM_1597
Hypothetical protein; Catalyzes the interconversion of D-lysine and L-lysine. Has also high activity toward ornithine, and weaker activity toward alanine. Contributes to production of D-lysine and D-alanine for use as peptidoglycan components.
       0.640
TM_1594
Conserved hypothetical protein, GGDEF domain; Similar to GB:AE000657 percent identity: 60.77; identified by sequence similarity; putative.
  
    0.479
TM_0155
Chorismate mutase/prephenate dehydratase; Similar to GB:AE000782 percent identity: 80.45; identified by sequence similarity; putative.
   
 
 0.470
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.468
TM_1595
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 58.22; identified by sequence similarity; putative.
       0.467
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.