Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TM_1624Beta-mannosidase, putative; Similar to PID:1621036 percent identity: 53.79; identified by sequence similarity; putative; Belongs to the glycosyl hydrolase 2 family. (785 aa)    
Predicted Functional Partners:
TM_0281
alpha-L-arabinofuranosidase; Similar to SP:P94531 PID:1770022 PID:1913931 GB:AL009126 percent identity: 58.66; identified by sequence similarity; putative.
 
  
 0.697
lepA
lepA protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
     0.669
TM_1621
Hypothetical protein; Identified by sequence similarity; putative.
  
    0.568
TM_0306
alpha-L-fucosidase, putative; Similar to GB:M29877 SP:P04066 PID:1335066 PID:178409 PID:182779 percent identity: 56.91; identified by sequence similarity; putative.
 
   
 0.562
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.561
TM_1620
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
       0.560
TM_1622
Hypothetical protein; Identified by sequence similarity; putative.
       0.560
cheX
cheX protein; Involved in restoring normal CheY-P levels by dephosphorylating CheY-P. It has a greater activity than CheC; Belongs to the CheC family.
       0.546
TM_1227
Endo-1,4-beta-mannosidase; Similar to PID:1679597 percent identity: 54.44; identified by sequence similarity; putative.
 
  
 0.517
TM_1851
Alpha-mannosidase, putative; Similar to PID:1001414 PID:1001401 percent identity: 57.81; identified by sequence similarity; putative.
  
   
 0.517
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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